A news item in Nature by Ariana Remmel explains how challenging it is to prove that a medical problem following immunization was caused by the vaccine itself and describes the kinds of studies that are needed to understand the causes of rare adverse events. These include targeted clinical trials and active surveillance systems that collect adverse event data, both background rates and rates after vaccination, from electronic health records.
- Mix-and-match COVID vaccines trigger potent immune response May 24, 2021
- Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca in Denmark and Norway May 12, 2021
- The critical role of background rates of possible adverse events in the assessment of COVID-19 vaccine safety April 17, 2021
- The UK Expert Haematology Panel (EHP) has produced guidance on the syndrome of Thrombosis and Thrombocytopenia occurring after coronavirus vaccination April 8, 2021
- Why is it so hard to investigate the rare side effects of COVID vaccines? April 7, 2021